Orbital malignant peripheral nerve sheath tumours.
نویسندگان
چکیده
منابع مشابه
Adjuvant Treatment For Patients With Malignant Peripheral Nerve Sheath Tumours
Matthias Kolberg1,2,3 Sigbjørn Smeland2,4 and Ragnhild A Lothe1,2,3,4* 1Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, Oslo Norway 2Clinic for Cancer Medicine, Surgery and Transplantation, Oslo University Hospital, Oslo, Norway 3Center of Cancer Biomedicine, University of Oslo, Oslo Norway 4Institute of Clinical Medicine, University of Oslo, Oslo, Norway
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Malignant peripheral nerve sheath tumours (MPNST) are aggressive sarcomas that develop in about 10% of patients with the genetic disease neurofibromatosis type 1 (NF1). Molecular alterations contributing to MPNST formation have only partially been resolved. Here we examined the role of Pten, a key regulator of the Pi3k/Akt/mTOR pathway, in human MPNST and benign neurofibromas. Immunohistochemis...
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Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0.001% in general population and 0.16% in patients with neurofibromatosis I (NF I). We report a case of 60 year female presenting with progressive cough and breathlessne...
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Samples of morbid bovine tissues obtained from slaughterhouse were submitted to histopathological examination. Neoplastic growth within the peripheral nerves was observed microscopically, with the presence of Antoni A and Antoni B patterns, and sporadically Verocay bodies. Additionally, immunohistochemical examination of the sections revealed positive reaction to vimentine, neuron specific enol...
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A 40-year-old man presented with complaints of left-sided lower back discomfort for 2 to 3 months. There was no other significant history. Physical examination was unremarkable except for a palpable mass in the left flank. Ultrasonography showed a hypoechoic mass. Biphasic contrast-enhanced computerized tomogram revealed a large, heterogenous, infiltrating, necrotic mass lesion arising from the...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1989
ISSN: 0007-1161
DOI: 10.1136/bjo.73.9.731